In vivo translational assessment of the GES genotype on the killing profile of ceftazidime, ceftazidime/avibactam and meropenem against Pseudomonas aeruginosa

OBJECTIVES: To evaluate the in vivo killing profile of human-simulated exposures of ceftazidime, ceftazidime/avibactam and meropenem against GES-harbouring Pseudomonas aeruginosa in the murine thigh infection model. METHODS: Five P. aeruginosa isolates [three isogenic (GES-1, GES-5 and GES-15) and t...

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Detalles Bibliográficos
Autores principales: Gill, Christian M, Oliver, Antonio, Fraile-Ribot, Pablo Arturo, Nicolau, David P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9525071/
https://www.ncbi.nlm.nih.gov/pubmed/35848936
http://dx.doi.org/10.1093/jac/dkac232

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9525071/
https://www.ncbi.nlm.nih.gov/pubmed/35848936
http://dx.doi.org/10.1093/jac/dkac232

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