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In vivo translational assessment of the GES genotype on the killing profile of ceftazidime, ceftazidime/avibactam and meropenem against Pseudomonas aeruginosa

OBJECTIVES: To evaluate the in vivo killing profile of human-simulated exposures of ceftazidime, ceftazidime/avibactam and meropenem against GES-harbouring Pseudomonas aeruginosa in the murine thigh infection model. METHODS: Five P. aeruginosa isolates [three isogenic (GES-1, GES-5 and GES-15) and t...

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Detalles Bibliográficos
Autores principales:	Gill, Christian M, Oliver, Antonio, Fraile-Ribot, Pablo Arturo, Nicolau, David P
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9525071/ https://www.ncbi.nlm.nih.gov/pubmed/35848936 http://dx.doi.org/10.1093/jac/dkac232

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