TDO2(+) myofibroblasts mediate immune suppression in malignant transformation of squamous cell carcinoma

Characterization of the dynamic change in the immunological landscape during malignant transformation from precancerous lesions to cancerous lesions in squamous cell carcinoma (SCC) is critical for the application of immunotherapy. Here, we performed single-cell RNA-Seq (scRNA-Seq) of 131,702 cells...

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Detalles Bibliográficos
Autores principales: Hu, Simeng, Lu, Huanzi, Xie, Wenqiang, Wang, Dikan, Shan, Zhongyan, Xing, Xudong, Wang, Xiang-Ming, Fang, Juan, Dong, Wei, Dai, Wenxiao, Guo, Junyi, Zhang, Yanshu, Wen, Shuqiong, Guo, Xin-Yu, Chen, Qianming, Bai, Fan, Wang, Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9525123/
https://www.ncbi.nlm.nih.gov/pubmed/35972800
http://dx.doi.org/10.1172/JCI157649

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9525123/
https://www.ncbi.nlm.nih.gov/pubmed/35972800
http://dx.doi.org/10.1172/JCI157649

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