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The DPY30-H3K4me3 Axis-Mediated PD-L1 Expression in Melanoma

BACKGROUND: DPY30 is a common subunit of the human SET1/MLL complex and is an essential protein required for the activity of SET1/MLL methyltransferase. DPY30 regulates the histone H3K4 modification, and dysfunction of DPY30 might contribute to the regulation of cancer immune evasion. However, the f...

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Detalles Bibliográficos
Autores principales: Zhang, Zhichun, Han, Yixuan, Sun, Qiuyue, Wang, Yipeng, Sun, Lichao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9525212/
https://www.ncbi.nlm.nih.gov/pubmed/36185638
http://dx.doi.org/10.2147/JIR.S377678