Cargando…

StackPR is a new computational approach for large-scale identification of progesterone receptor antagonists using the stacking strategy

Progesterone receptors (PRs) are implicated in various cancers since their presence/absence can determine clinical outcomes. The overstimulation of progesterone can facilitate oncogenesis and thus, its modulation through PR inhibition is urgently needed. To address this issue, a novel stacked ensemb...

Descripción completa

Detalles Bibliográficos
Autores principales: Schaduangrat, Nalini, Anuwongcharoen, Nuttapat, Moni, Mohammad Ali, Lio’, Pietro, Charoenkwan, Phasit, Shoombuatong, Watshara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9525257/
https://www.ncbi.nlm.nih.gov/pubmed/36180453
http://dx.doi.org/10.1038/s41598-022-20143-5