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FX5, a non-steroidal glucocorticoid receptor antagonist, ameliorates diabetic cognitive impairment in mice

Diabetic cognitive impairment (DCI) is a common diabetic complication characterized by learning and memory deficits. In diabetic patients, hyperactivated hypothalamic-pituitary-adrenal (HPA) axis leads to abnormal increase of glucocorticoids (GCs), which causes the damage of hippocampal neurons and...

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Detalles Bibliográficos
Autores principales: Zhu, Dan-yang, Lu, Jian, Xu, Rui, Yang, Juan-zhen, Meng, Xiang-rui, Ou-Yang, Xing-nan, Yan, Qiu-ying, Nie, Rui-fang, Zhao, Tong, Chen, Yi-di, Lu, Yin, Zhang, Yi-nan, Li, Wen-jun, Shen, Xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9525278/
https://www.ncbi.nlm.nih.gov/pubmed/35260821
http://dx.doi.org/10.1038/s41401-022-00884-9