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Stimulation of de novo glutathione synthesis by nitrofurantoin for enhanced resilience of hepatocytes
Toxicity is not only a function of damage mechanisms, but is also determined by cellular resilience factors. Glutathione has been reported as essential element to counteract negative influences. The present work hence pursued the question how intracellular glutathione can be elevated transiently to...
Autores principales: | Wijaya, Lukas S., Rau, Carina, Braun, Theresa S., Marangoz, Serif, Spegg, Vincent, Vlasveld, Matthijs, Albrecht, Wiebke, Brecklinghaus, Tim, Kamp, Hennicke, Beltman, Joost B., Hengstler, Jan G., van de Water, Bob, Leist, Marcel, Schildknecht, Stefan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9525367/ https://www.ncbi.nlm.nih.gov/pubmed/34021431 http://dx.doi.org/10.1007/s10565-021-09610-3 |
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