Sulfur mustard single-dose exposure triggers senescence in primary human dermal fibroblasts

Chronic wounds, skin blisters, and ulcers are the result of skin exposure to the alkylating agent sulfur mustard (SM). One potential pathomechanism is senescence, which causes permanent growth arrest with a pro-inflammatory environment and may be associated with a chronic wound healing disorder. SM...

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Detalles Bibliográficos
Autores principales: Horn, Gabriele, Schäfers, Catherine, Thiermann, Horst, Völkl, Sandra, Schmidt, Annette, Rothmiller, Simone
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Organ Toxicity and Mechanisms
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9525386/
https://www.ncbi.nlm.nih.gov/pubmed/35906424
http://dx.doi.org/10.1007/s00204-022-03346-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9525386/
https://www.ncbi.nlm.nih.gov/pubmed/35906424
http://dx.doi.org/10.1007/s00204-022-03346-7

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