Repair of α-particle-induced DNA damage in peripheral blood mononuclear cells after internal ex vivo irradiation with (223)Ra

PURPOSE: As α-emitters for radiopharmaceutical therapies are administered systemically by intravenous injection, blood will be irradiated by α-particles that induce clustered DNA double-strand breaks (DSBs). Here, we investigated the induction and repair of DSB damage in peripheral blood mononuclear...

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Detalles Bibliográficos
Autores principales: Göring, Lukas, Schumann, Sarah, Müller, Jessica, Buck, Andreas K., Port, Matthias, Lassmann, Michael, Scherthan, Harry, Eberlein, Uta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9525426/
https://www.ncbi.nlm.nih.gov/pubmed/35759008
http://dx.doi.org/10.1007/s00259-022-05860-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9525426/
https://www.ncbi.nlm.nih.gov/pubmed/35759008
http://dx.doi.org/10.1007/s00259-022-05860-3

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