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Impact of radiopharmaceutical therapy ((177)Lu, (225)Ac) microdistribution in a cancer-associated fibroblasts model

BACKGROUND: The aim of this study is to elucidate the difference in absorbed dose (D(abs)) patterns in radiopharmaceutical therapies between alpha emitters ((225)Ac) and beta emitters ((177)Lu) when targeting cancer-associated fibroblasts (CAF) or tumor cells. Five spherical models with 3 mm diamete...

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Detalles Bibliográficos
Autores principales: Tranel, Jonathan, Palm, Stig, Graves, Stephen A., Feng, Felix Y., Hope, Thomas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9525486/
https://www.ncbi.nlm.nih.gov/pubmed/36178531
http://dx.doi.org/10.1186/s40658-022-00497-5