Cargando…

CTLA-4-Ig internalizes CD80 in fibroblast-like synoviocytes from chronic inflammatory arthritis mouse model

CD80 interact with CD28 and CTLA-4 on antigen-presenting cells, and function in the co-stimulatory signaling that regulates T cell activity. CTLA-4-Ig is used to treat RA by blocking co-stimulatory signaling. Chronic inflammatory arthritis was induced in D1BC mice using low-dose arthritogenic antige...

Descripción completa

Detalles Bibliográficos
Autores principales:	Miura, Yoko, Isogai, Shyuntaro, Maeda, Shinji, Kanazawa, Satoshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9525600/ https://www.ncbi.nlm.nih.gov/pubmed/36180526 http://dx.doi.org/10.1038/s41598-022-20694-7

Ejemplares similares

Osteochondrogenesis derived from synovial fibroblasts in inflammatory arthritis model
por: Miura, Yoko, et al.
Publicado: (2020)

Fibroblast-like synoviocyte metabolism in the pathogenesis of rheumatoid arthritis
por: Bustamante, Marta F., et al.
Publicado: (2017)

Impact of Single-Nucleotide Polymorphisms of CTLA-4, CD80 and CD86 on the Effectiveness of Abatacept in Patients with Rheumatoid Arthritis
por: Marquez Pete, Noelia, et al.
Publicado: (2020)

Chemerin activates fibroblast-like synoviocytes in patients with rheumatoid arthritis
por: Kaneko, Kayoko, et al.
Publicado: (2011)

Comprehensive epigenetic landscape of rheumatoid arthritis fibroblast-like synoviocytes
por: Ai, Rizi, et al.
Publicado: (2018)

Cyclophilin A secreted from fibroblast-like synoviocytes is involved in the induction of CD147 expression in macrophages of mice with collagen-induced arthritis
por: Nishioku, Tsuyoshi, et al.
Publicado: (2012)

The Association Between CTLA-4, CD80/86, and CD28 Gene Polymorphisms and Rheumatoid Arthritis: An Original Study and Meta-Analysis
por: Liu, Weixi, et al.
Publicado: (2021)

CD147 overexpression on synoviocytes in rheumatoid arthritis enhances matrix metalloproteinase production and invasiveness of synoviocytes
por: Zhu, Ping, et al.
Publicado: (2006)

Suppression of epithelial abnormalities by nintedanib in induced-rheumatoid arthritis-associated interstitial lung disease mouse model
por: Miura, Yoko, et al.
Publicado: (2021)

Metabolomic Elucidation of the Effects of Curcumin on Fibroblast-Like Synoviocytes in Rheumatoid Arthritis
por: Ahn, Joong Kyong, et al.
Publicado: (2015)

Oridonin suppresses autophagy and survival in rheumatoid arthritis fibroblast-like synoviocytes
por: He, Shou-Di, et al.
Publicado: (2020)

Solute carrier nutrient transporters in rheumatoid arthritis fibroblast-like synoviocytes
por: Torres, Alyssa, et al.
Publicado: (2022)

Differences in CD80 and CD86 transendocytosis reveal CD86 as a key target for CTLA-4 immune regulation
por: Kennedy, Alan, et al.
Publicado: (2022)

Blood PD-1(+)TFh and CTLA-4(+)CD4(+) T cells predict remission after CTLA-4Ig treatment in early rheumatoid arthritis
por: Aldridge, Jonathan, et al.
Publicado: (2021)

Cytotoxic T lymphocyte-associated antigen-4-Ig (CTLA-4-Ig) suppresses Staphylococcus aureus-induced CD80, CD86, and pro-inflammatory cytokine expression in human B cells
por: Liu, Po-Chun, et al.
Publicado: (2020)

TRAIL-induced rheumatoid arthritis fibroblast-like synoviocyte proliferation is inhibited by OPG
por: Morel, J, et al.
Publicado: (2004)

15-Hydroxyprostaglandin dehydrogenase is upregulated by hydroxychloroquine in rheumatoid arthritis fibroblast-like synoviocytes
por: KIM, HAK-JAE, et al.
Publicado: (2015)

Thioredoxin 1 is associated with the proliferation and apoptosis of rheumatoid arthritis fibroblast-like synoviocytes
por: Lu, Tianbao, et al.
Publicado: (2017)

RHAMM induces progression of rheumatoid arthritis by enhancing the functions of fibroblast-like synoviocytes
por: Wu, Jing, et al.
Publicado: (2018)

Fibroblast-Like Synoviocytes Glucose Metabolism as a Therapeutic Target in Rheumatoid Arthritis
por: de Oliveira, Patricia Gnieslaw, et al.
Publicado: (2019)

Expression of AIM2 in Rheumatoid Arthritis and Its Role on Fibroblast-Like Synoviocytes
por: Chen, Yong, et al.
Publicado: (2020)

NF-κB signaling in rheumatoid arthritis with focus on fibroblast-like synoviocytes
por: Nejatbakhsh Samimi, Leila, et al.
Publicado: (2020)

Quercetin suppresses inflammatory cytokine production in rheumatoid arthritis fibroblast-like synoviocytes
por: Sun, Hai-Tao, et al.
Publicado: (2021)

Tofacitinib Decreases Autophagy of Fibroblast-Like Synoviocytes From Rheumatoid Arthritis Patients
por: Vomero, M., et al.
Publicado: (2022)

Transformation of fibroblast‐like synoviocytes in rheumatoid arthritis; from a friend to foe
por: Mousavi, Mohammad Javad, et al.
Publicado: (2021)

PTEN Methylation Promotes Inflammation and Activation of Fibroblast-Like Synoviocytes in Rheumatoid Arthritis
por: Li, Xiao-Feng, et al.
Publicado: (2021)

Role of mitochondria-bound HK2 in rheumatoid arthritis fibroblast-like synoviocytes
por: Torres, Alyssa, et al.
Publicado: (2023)

Role and mechanism of fibroblast-activated protein-α expression on the surface of fibroblast-like synoviocytes in rheumatoid arthritis
por: Wang, Zihan, et al.
Publicado: (2023)

Immune suppression in cynomolgus monkeys by XPro9523: An improved CTLA4-Ig fusion with enhanced binding to CD80, CD86 and neonatal Fc receptor FcRn
por: Bernett, Matthew J., et al.
Publicado: (2013)

Effects of inflammatory cytokine IL-27 on the activation of fibroblast-like synoviocytes in rheumatoid arthritis
por: Wong, Chun K, et al.
Publicado: (2010)

Innate immunity triggers IL-32 expression by fibroblast-like synoviocytes in rheumatoid arthritis
por: Alsaleh, Ghada, et al.
Publicado: (2010)

Anti-Inflammatory Effects of TRAF-Interacting Protein in Rheumatoid Arthritis Fibroblast-Like Synoviocytes
por: Kong, Qing-Zhu, et al.
Publicado: (2016)

Resistin upregulates chemokine production by fibroblast-like synoviocytes from patients with rheumatoid arthritis
por: Sato, Hiroshi, et al.
Publicado: (2017)

Functional role of PPAR-γ on the proliferation and migration of fibroblast-like synoviocytes in rheumatoid arthritis
por: Li, Xiao-Feng, et al.
Publicado: (2017)

Kirenol Inhibits the Function and Inflammation of Fibroblast-like Synoviocytes in Rheumatoid Arthritis in vitro and in vivo
por: Wu, Jing, et al.
Publicado: (2019)

Increased autophagy in fibroblast-like synoviocytes leads to immune enhancement potential in rheumatoid arthritis
por: Yang, Ru, et al.
Publicado: (2016)

Inhibition of BMP3 increases the inflammatory response of fibroblast-like synoviocytes in rheumatoid arthritis
por: Song, Biao, et al.
Publicado: (2020)

Joint Location–Specific JAK‐STAT Signaling in Rheumatoid Arthritis Fibroblast‐like Synoviocytes
por: Hammaker, Deepa, et al.
Publicado: (2019)

A two-herb formula inhibits hyperproliferation of rheumatoid arthritis fibroblast-like synoviocytes
por: Chen, Ying-Jie, et al.
Publicado: (2021)

Phenotypic and functional characterization of synovial fluid-derived fibroblast-like synoviocytes in rheumatoid arthritis
por: Køster, Ditte, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_u8h68tnkuva3uj7n63o2jmloum