Single cell and spatial transcriptomic analyses reveal microglia-plasma cell crosstalk in the brain during Trypanosoma brucei infection

Human African trypanosomiasis, or sleeping sickness, is caused by the protozoan parasite Trypanosoma brucei and induces profound reactivity of glial cells and neuroinflammation when the parasites colonise the central nervous system. However, the transcriptional and functional responses of the brain...

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Detalles Bibliográficos
Autores principales: Quintana, Juan F., Chandrasegaran, Praveena, Sinton, Matthew C., Briggs, Emma M., Otto, Thomas D., Heslop, Rhiannon, Bentley-Abbot, Calum, Loney, Colin, de Lecea, Luis, Mabbott, Neil A., MacLeod, Annette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9525673/
https://www.ncbi.nlm.nih.gov/pubmed/36180478
http://dx.doi.org/10.1038/s41467-022-33542-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9525673/
https://www.ncbi.nlm.nih.gov/pubmed/36180478
http://dx.doi.org/10.1038/s41467-022-33542-z

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