Inositol hexakisphosphate is required for Integrator function

Integrator is a multi-subunit protein complex associated with RNA polymerase II (Pol II), with critical roles in noncoding RNA 3′-end processing and transcription attenuation of a broad collection of mRNAs. IntS11 is the endonuclease for RNA cleavage, as a part of the IntS4-IntS9-IntS11 Integrator c...

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Detalles Bibliográficos
Autores principales: Lin, Min-Han, Jensen, Madeline K., Elrod, Nathan D., Huang, Kai-Lieh, Welle, Kevin A., Wagner, Eric J., Tong, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9525679/
https://www.ncbi.nlm.nih.gov/pubmed/36180473
http://dx.doi.org/10.1038/s41467-022-33506-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9525679/
https://www.ncbi.nlm.nih.gov/pubmed/36180473
http://dx.doi.org/10.1038/s41467-022-33506-3

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