Cargando…

Inositol hexakisphosphate is required for Integrator function

Integrator is a multi-subunit protein complex associated with RNA polymerase II (Pol II), with critical roles in noncoding RNA 3′-end processing and transcription attenuation of a broad collection of mRNAs. IntS11 is the endonuclease for RNA cleavage, as a part of the IntS4-IntS9-IntS11 Integrator c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lin, Min-Han, Jensen, Madeline K., Elrod, Nathan D., Huang, Kai-Lieh, Welle, Kevin A., Wagner, Eric J., Tong, Liang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9525679/ https://www.ncbi.nlm.nih.gov/pubmed/36180473 http://dx.doi.org/10.1038/s41467-022-33506-3

Ejemplares similares

Inositol Pyrophosphate Synthesis by Inositol Hexakisphosphate Kinase 1 Is Required for Homologous Recombination Repair
por: Jadav, Rathan S., et al.
Publicado: (2013)

Broad Spectrum Anticancer Activity of Myo-Inositol and Inositol Hexakisphosphate
por: Bizzarri, Mariano, et al.
Publicado: (2016)

Inositol hexakisphosphate increases the size of platelet aggregates
por: Brehm, Maria A., et al.
Publicado: (2019)

Primate lentiviruses require Inositol hexakisphosphate (IP6) or inositol pentakisphosphate (IP5) for the production of viral particles
por: Ricana, Clifton L., et al.
Publicado: (2020)

Do mammals make all their own inositol hexakisphosphate?
por: Letcher, Andrew J., et al.
Publicado: (2008)

The Role of Inositol Hexakisphosphate Kinase in the Central Nervous System
por: Heitmann, Tyler, et al.
Publicado: (2023)

Inositol Hexakisphosphate-Induced Autoprocessing of Large Bacterial Protein Toxins
por: Egerer, Martina, et al.
Publicado: (2010)

Inositol Hexakisphosphate Kinase 3 Regulates Metabolism and Lifespan in Mice
por: Moritoh, Yusuke, et al.
Publicado: (2016)

Autoinhibition of Bruton's tyrosine kinase (Btk) and activation by soluble inositol hexakisphosphate
por: Wang, Qi, et al.
Publicado: (2015)

The enzymatic activity of inositol hexakisphosphate kinase controls circulating phosphate in mammals
por: Moritoh, Yusuke, et al.
Publicado: (2021)

Inositol hexakisphosphate primes syndapin I/PACSIN 1 activation in endocytosis
por: Shi, Yue, et al.
Publicado: (2022)

An unconventional gatekeeper mutation sensitizes inositol hexakisphosphate kinases to an allosteric inhibitor
por: Aguirre, Tim, et al.
Publicado: (2023)

Phytate (Inositol Hexakisphosphate) in Soil and Phosphate Acquisition from Inositol Phosphates by Higher Plants. A Review
por: Gerke, Jörg
Publicado: (2015)

Inositol hexakisphosphate kinase 1 (IP6K1) activity is required for cytoplasmic dynein-driven transport
por: Chanduri, Manasa, et al.
Publicado: (2016)

Multiple aspects of male germ cell development and interactions with Sertoli cells require inositol hexakisphosphate kinase-1
por: Fu, Chenglai, et al.
Publicado: (2018)

Inositol hexakisphosphate kinase 1 is a metabolic sensor in pancreatic β-cells
por: Rajasekaran, Subu Surendran, et al.
Publicado: (2018)

Simple synthesis of (32)P-labelled inositol hexakisphosphates for study of phosphate transformations
por: Whitfield, Hayley, et al.
Publicado: (2017)

Malignant H1299 tumour cells preferentially internalize iron-bound inositol hexakisphosphate
por: Helmis, Christina, et al.
Publicado: (2013)

MINPP1 prevents intracellular accumulation of the chelator inositol hexakisphosphate and is mutated in Pontocerebellar Hypoplasia
por: Ucuncu, Ekin, et al.
Publicado: (2020)

Evaluation of in vitro and in vivo biocompatibility of a myo-inositol hexakisphosphate gelated polyaniline hydrogel in a rat model
por: Sun, Kwang-Hsiao, et al.
Publicado: (2016)

Influence of pH on the Cytotoxic Activity of Inositol Hexakisphosphate (IP6) in Prostate Cancer
por: Betton, Blandine, et al.
Publicado: (2011)

Inositol Hexakisphosphate Inhibits Osteoclastogenesis on RAW 264.7 Cells and Human Primary Osteoclasts
por: Arriero, María del Mar, et al.
Publicado: (2012)

Development of a homogenous high-throughput assay for inositol hexakisphosphate kinase 1 activity
por: Wormald, Michael, et al.
Publicado: (2017)

Inositol hexakisphosphate kinases differentially regulate trafficking of vesicular glutamate transporters 1 and 2
por: Li, Haiyan, et al.
Publicado: (2022)

Impacts of dietary calcium, phytate, and phytase on inositol hexakisphosphate degradation and inositol phosphate release in different segments of digestive tract of broilers
por: Li, W., et al.
Publicado: (2017)

Inositol hexakisphosphate kinase-1 is a key mediator of prepulse inhibition and short-term fear memory
por: Kim, Min-Gyu, et al.
Publicado: (2020)

Determination of neo- and d-chiro-Inositol Hexakisphosphate in Soils by Solution (31)P NMR Spectroscopy
por: Turner, Benjamin L., et al.
Publicado: (2012)

High‐resolution mass spectrometric analysis of myo‐inositol hexakisphosphate using electrospray ionisation Orbitrap
por: McIntyre, Catherine A., et al.
Publicado: (2017)

Atomic-scale characterization of mature HIV-1 capsid stabilization by inositol hexakisphosphate (IP(6))
por: Yu, Alvin, et al.
Publicado: (2020)

Inositol hexakisphosphate kinase-2 non-catalytically regulates mitophagy by attenuating PINK1 signaling
por: Nagpal, Latika, et al.
Publicado: (2022)

Enhanced killing of androgen-independent prostate cancer cells using inositol hexakisphosphate in combination with proteasome inhibitors
por: Diallo, J-S, et al.
Publicado: (2008)

The Acetyltransferase Activity of the Bacterial Toxin YopJ of Yersinia Is Activated by Eukaryotic Host Cell Inositol Hexakisphosphate
por: Mittal, Rohit, et al.
Publicado: (2010)

Pharmacological Inhibition of Inositol Hexakisphosphate Kinase 1 Protects Mice against Obesity-Induced Bone Loss
por: Boregowda, Siddaraju V., et al.
Publicado: (2022)

Lactic Acid and Thermal Treatments Trigger the Hydrolysis of Myo-Inositol Hexakisphosphate and Modify the Abundance of Lower Myo-Inositol Phosphates in Barley (Hordeum vulgare L.)
por: Metzler-Zebeli, Barbara U., et al.
Publicado: (2014)

Combined Inositol Hexakisphosphate and Inositol Supplement Consumption Improves Serum Alpha-Amylase Activity and Hematological Parameters in Streptozotocin-Induced Type 2 Diabetic Rats
por: Foster, Shadae R., et al.
Publicado: (2019)

Complexes of myo-inositol-hexakisphosphate (InsP6) with zinc or lanthanum to enhance excretion of radioactive strontium from the body
por: Ogawa, Kazuma, et al.
Publicado: (2018)

The Host Cell Metabolite Inositol Hexakisphosphate Promotes Efficient Endogenous HIV-1 Reverse Transcription by Stabilizing the Viral Capsid
por: Jennings, Jordan, et al.
Publicado: (2020)

Inositol Hexakisphosphate (IP6) Accelerates Immature HIV-1 Gag Protein Assembly toward Kinetically Trapped Morphologies
por: Pak, Alexander J., et al.
Publicado: (2022)

Fluoresceinated Aminohexanol Tethered Inositol Hexakisphosphate: Studies on Arabidopsis thaliana and Drosophila melanogaster and Docking with 2P1M Receptor
por: Thakur, Sujeet Kumar, et al.
Publicado: (2020)

Evidence for an inositol hexakisphosphate-dependent role for Ku in mammalian nonhomologous end joining that is independent of its role in the DNA-dependent protein kinase
por: Cheung, Joyce C.Y., et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_08j3kijsn9gk7j20okfubqnpts