Structural analysis of human CEACAM1 oligomerization

The human (h) CEACAM1 GFCC’ face serves as a binding site for homophilic and heterophilic interactions with various microbial and host ligands. hCEACAM1 has also been observed to form oligomers and micro-clusters on the cell surface which are thought to regulate hCEACAM1-mediated signaling. However,...

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Detalles Bibliográficos
Autores principales: Gandhi, Amit K., Sun, Zhen-Yu J., Huang, Yu-Hwa, Kim, Walter M., Yang, Chao, Petsko, Gregory A., Beauchemin, Nicole, Blumberg, Richard S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9525683/
https://www.ncbi.nlm.nih.gov/pubmed/36180783
http://dx.doi.org/10.1038/s42003-022-03996-4