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Mechanistic insight into the role of mevalonate kinase by a natural fatty acid-mediated killing of Leishmania donovani
We evaluated the anti-leishmanial efficacy of different saturated medium-chain fatty acids (FAs, C8–C18) where FA containing C8 chain, caprylic acid (CA), was found to be most potent against Leishmania donovani, the causative agent for visceral leishmaniasis (VL). Different analogs of CA with C8 lin...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9525708/ https://www.ncbi.nlm.nih.gov/pubmed/36180490 http://dx.doi.org/10.1038/s41598-022-20509-9 |