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Trimetazidine enhances myocardial angiogenesis in pressure overload-induced cardiac hypertrophy mice through directly activating Akt and promoting the binding of HSF1 to VEGF-A promoter

Latest clinical research shows that trimetazidine therapy during the perioperative period relieves endothelial dysfunction in patients with unstable angina induced by percutaneous coronary intervention. In this study we investigated the effects of TMZ on myocardial angiogenesis in pressure overload-...

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Detalles Bibliográficos
Autores principales: Shu, Hong-yang, Peng, Yi-zhong, Hang, Wei-jian, Zhang, Min, Shen, Lan, Wang, Dao-wen, Zhou, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9525722/
https://www.ncbi.nlm.nih.gov/pubmed/35217815
http://dx.doi.org/10.1038/s41401-022-00877-8