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Trimetazidine enhances myocardial angiogenesis in pressure overload-induced cardiac hypertrophy mice through directly activating Akt and promoting the binding of HSF1 to VEGF-A promoter
Latest clinical research shows that trimetazidine therapy during the perioperative period relieves endothelial dysfunction in patients with unstable angina induced by percutaneous coronary intervention. In this study we investigated the effects of TMZ on myocardial angiogenesis in pressure overload-...
Autores principales: | Shu, Hong-yang, Peng, Yi-zhong, Hang, Wei-jian, Zhang, Min, Shen, Lan, Wang, Dao-wen, Zhou, Ning |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Nature Singapore
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9525722/ https://www.ncbi.nlm.nih.gov/pubmed/35217815 http://dx.doi.org/10.1038/s41401-022-00877-8 |
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