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Multiomic Analysis Reveals Disruption of Cholesterol Homeostasis by Cannabidiol in Human Cell Lines

The nonpsychoactive cannabinoid, cannabidiol (CBD), is Food and Dug Administration approved for treatment of two drug-resistant epileptic disorders and is seeing increased use among the general public, yet the mechanisms that underlie its therapeutic effects and side-effect profiles remain unclear....

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Detalles Bibliográficos
Autores principales: Guard, Steven E., Chapnick, Douglas A., Poss, Zachary C., Ebmeier, Christopher C., Jacobsen, Jeremy, Nemkov, Travis, Ball, Kerri A., Webb, Kristofor J., Simpson, Helen L., Coleman, Stephen, Bunker, Eric, Ramirez, Adrian, Reisz, Julie A., Sievers, Robert, Stowell, Michael H.B., D’Alessandro, Angelo, Liu, Xuedong, Old, William M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9525918/
https://www.ncbi.nlm.nih.gov/pubmed/35753663
http://dx.doi.org/10.1016/j.mcpro.2022.100262