impMKT: the imputed McDonald and Kreitman test, a straightforward correction that significantly increases the evidence of positive selection of the McDonald and Kreitman test at the gene level

The McDonald and Kreitman test is one of the most powerful and widely used methods to detect and quantify recurrent natural selection in DNA sequence data. One of its main limitations is the underestimation of positive selection due to the presence of slightly deleterious variants segregating at low...

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Detalles Bibliográficos
Autores principales: Murga-Moreno, Jesús, Coronado-Zamora, Marta, Casillas, Sònia, Barbadilla, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9526038/
https://www.ncbi.nlm.nih.gov/pubmed/35976111
http://dx.doi.org/10.1093/g3journal/jkac206

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9526038/
https://www.ncbi.nlm.nih.gov/pubmed/35976111
http://dx.doi.org/10.1093/g3journal/jkac206

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