Exposure to low-dose perfluorooctanoic acid promotes hepatic steatosis and disrupts the hepatic transcriptome in mice

OBJECTIVE: Perfluoroalkyl substances (PFAS) are man-made chemicals with demonstrated endocrine-disrupting properties. Exposure to perfluorooctanoic acid (PFOA) has been linked to disturbed metabolism via the liver, although the exact mechanism is not clear. Moreover, information on the metabolic eff...

Descripción completa

Detalles Bibliográficos
Autores principales: Attema, Brecht, Janssen, Aafke W.F., Rijkers, Deborah, van Schothorst, Evert M., Hooiveld, Guido J.E.J., Kersten, Sander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9526138/
https://www.ncbi.nlm.nih.gov/pubmed/36115532
http://dx.doi.org/10.1016/j.molmet.2022.101602

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9526138/
https://www.ncbi.nlm.nih.gov/pubmed/36115532
http://dx.doi.org/10.1016/j.molmet.2022.101602

Ejemplares similares