Exposure to low-dose perfluorooctanoic acid promotes hepatic steatosis and disrupts the hepatic transcriptome in mice

OBJECTIVE: Perfluoroalkyl substances (PFAS) are man-made chemicals with demonstrated endocrine-disrupting properties. Exposure to perfluorooctanoic acid (PFOA) has been linked to disturbed metabolism via the liver, although the exact mechanism is not clear. Moreover, information on the metabolic eff...

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Detalles Bibliográficos
Autores principales: Attema, Brecht, Janssen, Aafke W.F., Rijkers, Deborah, van Schothorst, Evert M., Hooiveld, Guido J.E.J., Kersten, Sander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9526138/
https://www.ncbi.nlm.nih.gov/pubmed/36115532
http://dx.doi.org/10.1016/j.molmet.2022.101602

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