Adam10-dependent Notch signaling establishes dental epithelial cell boundaries required for enamel formation

The disintegrin and metalloproteinase Adam10 is a membrane-bound sheddase that regulates Notch signaling and ensures epidermal integrity. To address the function of Adam10 in the continuously growing incisors, we used Keratin14(Cre/+);Adam10(fl/fl) transgenic mice, in which Adam10 is conditionally d...

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Detalles Bibliográficos
Autores principales: Mitsiadis, Thimios A., Jimenez-Rojo, Lucia, Balic, Anamaria, Weber, Silvio, Saftig, Paul, Pagella, Pierfrancesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9526176/
https://www.ncbi.nlm.nih.gov/pubmed/36193048
http://dx.doi.org/10.1016/j.isci.2022.105154

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9526176/
https://www.ncbi.nlm.nih.gov/pubmed/36193048
http://dx.doi.org/10.1016/j.isci.2022.105154

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