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Adam10-dependent Notch signaling establishes dental epithelial cell boundaries required for enamel formation
The disintegrin and metalloproteinase Adam10 is a membrane-bound sheddase that regulates Notch signaling and ensures epidermal integrity. To address the function of Adam10 in the continuously growing incisors, we used Keratin14(Cre/+);Adam10(fl/fl) transgenic mice, in which Adam10 is conditionally d...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9526176/ https://www.ncbi.nlm.nih.gov/pubmed/36193048 http://dx.doi.org/10.1016/j.isci.2022.105154 |