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Seizures, ataxia and parvalbumin-expressing interneurons respond to selenium supply in Selenop-deficient mice
Mice with constitutive disruption of the Selenop gene have been key to delineate the importance of selenoproteins in neurobiology. However, the phenotype of this mouse model is exquisitely dependent on selenium supply and timing of selenium supplementation. Combining biochemical, histological, and b...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9526222/ https://www.ncbi.nlm.nih.gov/pubmed/36182809 http://dx.doi.org/10.1016/j.redox.2022.102490 |