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Seizures, ataxia and parvalbumin-expressing interneurons respond to selenium supply in Selenop-deficient mice

Mice with constitutive disruption of the Selenop gene have been key to delineate the importance of selenoproteins in neurobiology. However, the phenotype of this mouse model is exquisitely dependent on selenium supply and timing of selenium supplementation. Combining biochemical, histological, and b...

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Detalles Bibliográficos
Autores principales: Schweizer, Ulrich, Wirth, Eva K., Klopstock, Thomas, Hölter, Sabine M., Becker, Lore, Moskovitz, Jackob, Grune, Tilman, Fuchs, Helmut, Gailus-Durner, Valerie, Hrabe de Angelis, Martin, Köhrle, Josef, Schomburg, Lutz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9526222/
https://www.ncbi.nlm.nih.gov/pubmed/36182809
http://dx.doi.org/10.1016/j.redox.2022.102490