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Generation of vessel co-option lung metastases mouse models for single-cell isolation of metastases-derived cells and endothelial cells

Tumor vessel co-option, a process in which cancer cells “hijack” pre-existing blood vessels to grow and invade healthy tissue, is poorly understood but is a proposed resistance mechanism against anti-angiogenic therapy (AAT). Here, we describe protocols for establishing murine renal (RENCA) and brea...

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Detalles Bibliográficos
Autores principales: Cuypers, Anne, Teuwen, Laure-Anne, Bridgeman, Victoria L., de Rooij, Laura P.M.H., Eelen, Guy, Dewerchin, Mieke, Cantelmo, Anna Rita, Kalucka, Joanna, Bouché, Ann, Vinckier, Stefan, Carton, An, Manderveld, Ann, Vermeulen, Peter B., Reynolds, Andrew R., Carmeliet, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9526223/
https://www.ncbi.nlm.nih.gov/pubmed/36173713
http://dx.doi.org/10.1016/j.xpro.2022.101691