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RNA binding protein IGF2BP1 meditates oxidative stress-induced granulosa cell dysfunction by regulating MDM2 mRNA stability in an m(6)A-dependent manner

Both genetic and microenvironmental detrimental factors are involved in ovarian dysfunction, leading to the increasing rate of involuntary childlessness in recent years. Oxidative stress (OS), which is characterized by the imbalance of redox system with redundant reactive oxygen species (ROS) overwh...

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Detalles Bibliográficos
Autores principales: Mu, Hongbei, Cai, Siying, Wang, Xiaofei, Li, Huiying, Zhang, Ling, Li, Huaibiao, Xiang, Wenpei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9526231/
https://www.ncbi.nlm.nih.gov/pubmed/36182806
http://dx.doi.org/10.1016/j.redox.2022.102492