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RNA binding protein IGF2BP1 meditates oxidative stress-induced granulosa cell dysfunction by regulating MDM2 mRNA stability in an m(6)A-dependent manner
Both genetic and microenvironmental detrimental factors are involved in ovarian dysfunction, leading to the increasing rate of involuntary childlessness in recent years. Oxidative stress (OS), which is characterized by the imbalance of redox system with redundant reactive oxygen species (ROS) overwh...
Autores principales: | Mu, Hongbei, Cai, Siying, Wang, Xiaofei, Li, Huiying, Zhang, Ling, Li, Huaibiao, Xiang, Wenpei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9526231/ https://www.ncbi.nlm.nih.gov/pubmed/36182806 http://dx.doi.org/10.1016/j.redox.2022.102492 |
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