Cholesterol promotes clustering of PI(4,5)P(2) driving unconventional secretion of FGF2

FGF2 is a cell survival factor involved in tumor-induced angiogenesis that is secreted through an unconventional secretory pathway based upon direct protein translocation across the plasma membrane. Here, we demonstrate that both PI(4,5)P(2)-dependent FGF2 recruitment at the inner plasma membrane le...

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Detalles Bibliográficos
Autores principales: Lolicato, Fabio, Saleppico, Roberto, Griffo, Alessandra, Meyer, Annalena, Scollo, Federica, Pokrandt, Bianca, Müller, Hans-Michael, Ewers, Helge, Hähl, Hendrik, Fleury, Jean-Baptiste, Seemann, Ralf, Hof, Martin, Brügger, Britta, Jacobs, Karin, Vattulainen, Ilpo, Nickel, Walter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9526255/
https://www.ncbi.nlm.nih.gov/pubmed/36173379
http://dx.doi.org/10.1083/jcb.202106123

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9526255/
https://www.ncbi.nlm.nih.gov/pubmed/36173379
http://dx.doi.org/10.1083/jcb.202106123

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