Leveraging family history in genetic association analyses of binary traits

BACKGROUND: Considering relatives’ health history in logistic regression for case–control genome-wide association studies (CC-GWAS) may provide new information that increases accuracy and power to detect disease associated genetic variants. We conducted simulations and analyzed type 2 diabetes (T2D)...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Yixin, Meigs, James B., Liu, Ching-Ti, Dupuis, Josée, Sarnowski, Chloé
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9526325/
https://www.ncbi.nlm.nih.gov/pubmed/36182916
http://dx.doi.org/10.1186/s12864-022-08897-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9526325/
https://www.ncbi.nlm.nih.gov/pubmed/36182916
http://dx.doi.org/10.1186/s12864-022-08897-8

Ejemplares similares