RNA interference-mediated silencing of DNA methyltransferase 1 attenuates neuropathic pain by accelerating microglia M2 polarization

BACKGROUND: DNA methyltransferase 1 (DNMT1) exerts imperative functions in neuropathic pain (NP). This study explored the action of RNA interference-mediated DNMT1 silencing in NP by regulating microglial M2 polarization. METHODS: NP rat models were established using chronic constriction injury (CCI...

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Detalles Bibliográficos
Autores principales: Tan, Ying, Wang, Zongjiang, Liu, Tao, Gao, Peng, Xu, Shitao, Tan, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9526327/
https://www.ncbi.nlm.nih.gov/pubmed/36183073
http://dx.doi.org/10.1186/s12883-022-02860-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9526327/
https://www.ncbi.nlm.nih.gov/pubmed/36183073
http://dx.doi.org/10.1186/s12883-022-02860-6

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