Cargando…

RNA interference-mediated silencing of DNA methyltransferase 1 attenuates neuropathic pain by accelerating microglia M2 polarization

BACKGROUND: DNA methyltransferase 1 (DNMT1) exerts imperative functions in neuropathic pain (NP). This study explored the action of RNA interference-mediated DNMT1 silencing in NP by regulating microglial M2 polarization. METHODS: NP rat models were established using chronic constriction injury (CCI...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tan, Ying, Wang, Zongjiang, Liu, Tao, Gao, Peng, Xu, Shitao, Tan, Lei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9526327/ https://www.ncbi.nlm.nih.gov/pubmed/36183073 http://dx.doi.org/10.1186/s12883-022-02860-6

Ejemplares similares

Triptolide Attenuates Neuropathic Pain by Regulating Microglia Polarization through the CCL2/CCR2 Axis
por: Bao, Xubin, et al.
Publicado: (2021)

Microglia: sculptors of neuropathic pain?
por: Ward, Harry, et al.
Publicado: (2020)

Role of Microglia in Neuropathic Pain
por: Karavis, Miltiades Y, et al.
Publicado: (2023)

Lidocaine ameliorates chronic constriction injury-induced neuropathic pain through regulating M1/M2 microglia polarization
por: Yuan, Jiaqi, et al.
Publicado: (2022)

AEG-1 silencing attenuates M2-polarization of glioma-associated microglia/macrophages and sensitizes glioma cells to temozolomide
por: Li, Jing, et al.
Publicado: (2021)

Microglia in the spinal cord and neuropathic pain
por: Tsuda, Makoto
Publicado: (2015)

Short-chain fatty acids contribute to neuropathic pain via regulating microglia activation and polarization
por: Zhou, Feng, et al.
Publicado: (2021)

Purinergic signaling in microglia in the pathogenesis of neuropathic pain
por: INOUE, Kazuhide
Publicado: (2017)

EZH2 Methyltransferase Regulates Neuroinflammation and Neuropathic Pain
por: Weng, Han-Rong, et al.
Publicado: (2023)

Electroacupuncture attenuates spared nerve injury-induced neuropathic pain possibly by promoting the progression of AMPK/mTOR-mediated autophagy in spinal microglia
por: Cui, Yaomei, et al.
Publicado: (2022)

DNA Methylation: A Target in Neuropathic Pain
por: Jiang, Wei, et al.
Publicado: (2022)

GPR34 in spinal microglia exacerbates neuropathic pain in mice
por: Sayo, Akira, et al.
Publicado: (2019)

Normalization of cholesterol metabolism in spinal microglia alleviates neuropathic pain
por: Navia-Pelaez, Juliana M., et al.
Publicado: (2021)

Microglia-independent peripheral neuropathic pain in male and female mice
por: Tu, YuShan, et al.
Publicado: (2022)

Attenuation of Histone Methyltransferase KRYPTONITE-mediated transcriptional gene silencing by Geminivirus
por: Sun, Yan-Wei, et al.
Publicado: (2015)

Silencing of spinal Trpv1 attenuates neuropathic pain in rats by inhibiting CAMKII expression and ERK2 phosphorylation
por: Guo, Shao-Hui, et al.
Publicado: (2019)

Oleanolic acid administration alleviates neuropathic pain after a peripheral nerve injury by regulating microglia polarization-mediated neuroinflammation
por: Li, Xuyang, et al.
Publicado: (2020)

DKK3 ameliorates neuropathic pain via inhibiting ASK-1/JNK/p-38-mediated microglia polarization and neuroinflammation
por: Zhang, Long-Qing, et al.
Publicado: (2022)

DNA methyltransferase DNMT3a contributes to neuropathic pain by repressing Kcna2 in primary afferent neurons
por: Zhao, Jian-Yuan, et al.
Publicado: (2017)

Identification of Epigenetic Interactions between MicroRNA-30c-5p and DNA Methyltransferases in Neuropathic Pain
por: Francés, Raquel, et al.
Publicado: (2022)

Effects of hyperbaric oxygen therapy on neuropathic pain via mitophagy in microglia
por: Han, Guang, et al.
Publicado: (2017)

Neuropathic Pain: Biomolecular Intervention and Imaging via Targeting Microglia Activation
por: Ji, Aijun, et al.
Publicado: (2021)

Role of Microglia and Astrocytes in Spinal Cord Injury Induced Neuropathic Pain
por: Miranpuri, Gurwattan S., et al.
Publicado: (2021)

Microglia polarization in nociplastic pain: mechanisms and perspectives
por: Atta, Ahd A., et al.
Publicado: (2023)

Lentiviral-mediated inducible silencing of TLR4 attenuates neuropathic pain in a rat model of chronic constriction injury
por: Liu, Yantao, et al.
Publicado: (2018)

Intrathecal Infusion of Hydrogen-Rich Normal Saline Attenuates Neuropathic Pain via Inhibition of Activation of Spinal Astrocytes and Microglia in Rats
por: Ge, Yanhu, et al.
Publicado: (2014)

Caffeic acid phenethyl ester attenuates neuropathic pain by suppressing the p38/NF-κB signal pathway in microglia
por: Cheng, Hao, et al.
Publicado: (2018)

Dual HDAC/BRD4 Inhibitors Relieves Neuropathic Pain by Attenuating Inflammatory Response in Microglia After Spared Nerve Injury
por: Borgonetti, Vittoria, et al.
Publicado: (2022)

Molecular Hydrogen Attenuates Neuropathic Pain in Mice
por: Kawaguchi, Masanori, et al.
Publicado: (2014)

Transcranial direct current stimulation regulates phenotypic transformation of microglia to relieve neuropathic pain induced by spinal cord injury
por: Tan, Mingliang, et al.
Publicado: (2023)

Contribution of microglia and astrocytes to the central sensitization, inflammatory and neuropathic pain in the juvenile rat
por: Ikeda, Hiroshi, et al.
Publicado: (2012)

The Role of Satellite Glial Cells, Astrocytes, and Microglia in Oxaliplatin-Induced Neuropathic Pain
por: Lee, Ji Hwan, et al.
Publicado: (2020)

ATP-releasing SWELL1 channel in spinal microglia contributes to neuropathic pain
por: Chu, Jiachen, et al.
Publicado: (2023)

Bibliometric and visual analysis of microglia-related neuropathic pain from 2000 to 2021
por: Zhang, Shun-Bai, et al.
Publicado: (2023)

Dihydromyricetin attenuates neuropathic pain via enhancing the transition from M1 to M2 phenotype polarization by potentially elevating ALDH2 activity in vitro and vivo
por: Zhang, Wei, et al.
Publicado: (2020)

Correction: Intrathecal Infusion of Hydrogen-Rich Normal Saline Attenuates Neuropathic Pain via Inhibition of Activation of Spinal Astrocytes and Microglia in Rats
Publicado: (2014)

Author Correction: DNA methyltransferase DNMT3a contributes to neuropathic pain by repressing Kcna2 in primary afferent neurons
por: Zhao, Jian-Yuan, et al.
Publicado: (2020)

Parthenolide Relieves Pain and Promotes M2 Microglia/Macrophage Polarization in Rat Model of Neuropathy
por: Popiolek-Barczyk, Katarzyna, et al.
Publicado: (2015)

Minocycline selectively inhibits M1 polarization of microglia
por: Kobayashi, K, et al.
Publicado: (2013)

Biochanin-A attenuates neuropathic pain in diabetic rats
por: Chundi, Venkateswarlu, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_l1m350ia7ren31ba3h5fftjlof