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Huc-MSC-derived exosomes modified with the targeting peptide of aHSCs for liver fibrosis therapy

BACKGROUND: Effective therapeutics to stop or reverse liver fibrosis have not emerged, because these potential agents cannot specifically target activated hepatic stellate cells (aHSCs) or are frequently toxic to parenchymal cells. Human umbilical cord mesenchymal stem cell (Huc-MSC)-derived exosome...

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Detalles Bibliográficos
Autores principales: Lin, Yan, Yan, Mengchao, Bai, Zhongtian, Xie, Ye, Ren, Longfei, Wei, Jiayun, Zhu, Dan, Wang, Haiping, Liu, Yonggang, Luo, Junqian, Li, Xun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9526331/
https://www.ncbi.nlm.nih.gov/pubmed/36183106
http://dx.doi.org/10.1186/s12951-022-01636-x