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Huc-MSC-derived exosomes modified with the targeting peptide of aHSCs for liver fibrosis therapy
BACKGROUND: Effective therapeutics to stop or reverse liver fibrosis have not emerged, because these potential agents cannot specifically target activated hepatic stellate cells (aHSCs) or are frequently toxic to parenchymal cells. Human umbilical cord mesenchymal stem cell (Huc-MSC)-derived exosome...
Autores principales: | Lin, Yan, Yan, Mengchao, Bai, Zhongtian, Xie, Ye, Ren, Longfei, Wei, Jiayun, Zhu, Dan, Wang, Haiping, Liu, Yonggang, Luo, Junqian, Li, Xun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9526331/ https://www.ncbi.nlm.nih.gov/pubmed/36183106 http://dx.doi.org/10.1186/s12951-022-01636-x |
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