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Impaired response of blood neutrophils to cell-death stimulus differentiates AQP4-IgG-seropositive NMOSD from MOGAD

BACKGROUND: In neuromyelitis optica spectrum disorders (NMOSD) and myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD), neutrophils are found in CNS lesions. We previously demonstrated that NMOSD neutrophils show functional deficiencies. Thus, we hypothesized that neutrophil accu...

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Detalles Bibliográficos
Autores principales: Schroeder-Castagno, Maria, Del Rio-Serrato, Alba, Wilhelm, Andreas, Romero-Suárez, Silvina, Schindler, Patrick, Alvarez-González, Cesar, Duchow, Ankelien-Solveig, Bellmann-Strobl, Judith, Ruprecht, Klemens, Hastermann, Maria, Grütz, Gerald, Wildemann, Brigitte, Jarius, Sven, Schmitz-Hübsch, Tanja, Paul, Friedemann, Infante-Duarte, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9526338/
https://www.ncbi.nlm.nih.gov/pubmed/36183103
http://dx.doi.org/10.1186/s12974-022-02600-0