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Impaired response of blood neutrophils to cell-death stimulus differentiates AQP4-IgG-seropositive NMOSD from MOGAD
BACKGROUND: In neuromyelitis optica spectrum disorders (NMOSD) and myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD), neutrophils are found in CNS lesions. We previously demonstrated that NMOSD neutrophils show functional deficiencies. Thus, we hypothesized that neutrophil accu...
Autores principales: | Schroeder-Castagno, Maria, Del Rio-Serrato, Alba, Wilhelm, Andreas, Romero-Suárez, Silvina, Schindler, Patrick, Alvarez-González, Cesar, Duchow, Ankelien-Solveig, Bellmann-Strobl, Judith, Ruprecht, Klemens, Hastermann, Maria, Grütz, Gerald, Wildemann, Brigitte, Jarius, Sven, Schmitz-Hübsch, Tanja, Paul, Friedemann, Infante-Duarte, Carmen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9526338/ https://www.ncbi.nlm.nih.gov/pubmed/36183103 http://dx.doi.org/10.1186/s12974-022-02600-0 |
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