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Mitochondria-Targeted Antioxidant Mitoquinone Maintains Mitochondrial Homeostasis through the Sirt3-Dependent Pathway to Mitigate Oxidative Damage Caused by Renal Ischemia/Reperfusion

Mitochondrial dysfunction is a critical factor contributing to oxidative stress and apoptosis in ischemia-reperfusion (I/R) diseases. Mitoquinone (MitoQ) is a mitochondria-targeted antioxidant whose potent anti-I/R injury capacity has been demonstrated in organs such as the heart and the intestine....

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Detalles Bibliográficos
Autores principales: Mao, Hu, Zhang, Ye, Xiong, Yufeng, Zhu, Zijing, Wang, Lei, Liu, Xiuheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9526615/
https://www.ncbi.nlm.nih.gov/pubmed/36193071
http://dx.doi.org/10.1155/2022/2213503