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Cefazolin/BMP-2-Loaded Mesoporous Silica Nanoparticles for the Repair of Open Fractures with Bone Defects

The study aimed to explore the feasibility of a nanodrug delivery system to treat open fractures with bone defects. We developed a cefazolin (Cef)/bone morphogenetic protein 2 (BMP-2)@mesoporous silica nanoparticle (MSN) delivery system; meanwhile, Cef/MBP-2@ poly(lactic-co-glycolic acid) (PLGA) was...

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Detalles Bibliográficos
Autores principales: Shen, Mingkui, Wang, Lulu, Feng, Li, Xu, Chuangye, Gao, Yi, Li, Sijing, Wu, Yulan, Pei, Guoxian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9526639/
https://www.ncbi.nlm.nih.gov/pubmed/36193077
http://dx.doi.org/10.1155/2022/8385456