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Jatrorrhizine Alleviates DSS-Induced Ulcerative Colitis by Regulating the Intestinal Barrier Function and Inhibiting TLR4/MyD88/NF-κB Signaling Pathway

BACKGROUND: Ulcerative colitis (UC), a kind of autoimmune disease with unknown etiology, has been troubling human physical and mental health. Jatrorrhizine (Jat) is a natural isoquinoline alkaloid isolated from Coptis Chinensis, which has been proved to have antibacterial, anti-inflammatory, and ant...

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Detalles Bibliográficos
Autores principales: Niu, Shengqi, Jing, Manyi, Wen, Jianxia, Wei, Shizhang, Li, Haotian, Li, Xing, Ma, Xiao, Zhao, Yanling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9526656/
https://www.ncbi.nlm.nih.gov/pubmed/36193153
http://dx.doi.org/10.1155/2022/3498310