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Identification of Interleukin-1-Beta Inhibitors in Gouty Arthritis Using an Integrated Approach Based on Network Pharmacology, Molecular Docking, and Cell Experiments

BACKGROUND: This study aimed to investigate the molecular mechanism of Tongfengding capsule (TFDC) in treating immune-inflammatory diseases of gouty arthritis (GA) and interleukin-1-beta (IL-1β) inhibitors by using network pharmacology, molecular docking, and cell experiments. METHODS: In this study...

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Detalles Bibliográficos
Autores principales: Zeng, Liying, Lin, Zekun, Kang, Pan, Zhang, Meng, Tang, Hongyu, Li, Miao, Xu, Kun, Liu, Yamei, Jiang, Ziyun, Huo, Shaochuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9526673/
https://www.ncbi.nlm.nih.gov/pubmed/36193152
http://dx.doi.org/10.1155/2022/2322417