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Exportin 4 depletion leads to nuclear accumulation of a subset of circular RNAs

Numerous RNAs are exported from the nucleus, abnormalities of which lead to cellular complications and diseases. How thousands of circular RNAs (circRNAs) are exported from the nucleus remains elusive. Here, we provide lines of evidence to demonstrate a link between the conserved Exportin 4 (XPO4) a...

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Detalles Bibliográficos
Autores principales: Chen, Liang, Wang, Yucong, Lin, Jiamei, Song, Zhenxing, Wang, Qinwei, Zhao, Wenfang, Wang, Yan, Xiu, Xiaoyu, Deng, Yuqi, Li, Xiuzhi, Li, Qiqi, Wang, Xiaolin, Li, Jingxin, Liu, Xu, Liu, Kunpeng, Zhou, Jincong, Li, Kuan, Liu, Yuchan, Liao, Shanhui, Deng, Qin, Xu, Chao, Sun, Qianwen, Wu, Shengzhou, Zhang, Kaiming, Guan, Min-Xin, Zhou, Tianhua, Sun, Fei, Cai, Xiujun, Huang, Chuan, Shan, Ge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9526749/
https://www.ncbi.nlm.nih.gov/pubmed/36182935
http://dx.doi.org/10.1038/s41467-022-33356-z