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A mouse model of vitiligo based on endogenous auto-reactive CD8 + T cell targeting skin melanocyte

Vitiligo is the most common human skin depigmenting disorder. It is mediated by endogenous autoreactive CD8 + T cells that destruct skin melanocytes. This disease has an estimated prevalence of 1% of the global population and currently has no cure. Animal models are indispensable tools for understan...

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Detalles Bibliográficos
Autores principales: Chen, Daoming, Xu, Zijian, Cui, Jun, Chen, Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9526765/
https://www.ncbi.nlm.nih.gov/pubmed/36182982
http://dx.doi.org/10.1186/s13619-022-00132-9