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Comparison of PSMA-TO-1 and PSMA-617 labeled with gallium-68, lutetium-177 and actinium-225

BACKGROUND: PSMA-TO-1 (“Tumor-Optimized-1”) is a novel PSMA ligand with longer circulation time than PSMA-617. We compared the biodistribution in subcutaneous tumor-bearing mice of PSMA-TO-1, PSMA-617 and PSMA-11 when labeled with (68)Ga and (177)Lu, and the survival after treatment with (225)Ac-PSM...

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Detalles Bibliográficos
Autores principales: Meyer, Catherine, Prasad, Vikas, Stuparu, Andreea, Kletting, Peter, Glatting, Gerhard, Miksch, Jonathan, Solbach, Christoph, Lueckerath, Katharina, Nyiranshuti, Lea, Zhu, Shaojun, Czernin, Johannes, Beer, Ambros J., Slavik, Roger, Calais, Jeremie, Dahlbom, Magnus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9526774/
https://www.ncbi.nlm.nih.gov/pubmed/36182983
http://dx.doi.org/10.1186/s13550-022-00935-6