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Dioscin ameliorates slow transit constipation in mice by up-regulation of the BMP2 secreted by muscularis macrophages

OBJECTIVE(S): The loss of enteric neurons has been shown to be a major cause of slow transit constipation (STC). Gut microbiota and muscularis macrophages (MMs) are associated with the enteric nervous system (ENS) development and gastrointestinal (GI) motility. This study aimed to investigate whethe...

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Detalles Bibliográficos
Autores principales: Ren, BingBing, Fu, SiQi, Liu, Yong, Kang, JianYu, Wang, Bo, Yao, ZhiWei, Wang, Hao, Sun, DaQing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9526884/
https://www.ncbi.nlm.nih.gov/pubmed/36246057
http://dx.doi.org/10.22038/IJBMS.2022.64683.14236