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Intra-mPFC injection of sodium butyrate promotes BDNF expression and ameliorates extinction recall impairment in an experimental paradigm of post-traumatic stress disorder

OBJECTIVE(S): Therapeutic strategies that facilitate extinction are promising in the treatment of post-traumatic stress disorder (PTSD). Brain-derived neurotrophic factor (BDNF) has a crucial role in neural plasticity, a process needed for the retention of fear extinction. In this study, we investig...

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Detalles Bibliográficos
Autores principales: Mohammadi-Farani, Ahmad, Fakhri, Sajad, Jalili, Cyrus, Samimi, Zahra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9526891/
https://www.ncbi.nlm.nih.gov/pubmed/36246060
http://dx.doi.org/10.22038/IJBMS.2022.65000.14312