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YAP1 protects against septic liver injury via ferroptosis resistance

BACKGROUND: The liver plays crucial roles in sepsis and is one of the major targets for sepsis-related injuries. Ferroptosis, a newly emerged form of lytic cell death, has been implicated in sepsis related organ failure. Yes-associated protein1 (YAP1), a key regulator of the Hippo signaling pathway,...

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Detalles Bibliográficos
Autores principales: Wang, Jin, Zhu, Qian, Li, Rui, Zhang, Jing, Ye, Xujun, Li, Xinyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9526934/
https://www.ncbi.nlm.nih.gov/pubmed/36182901
http://dx.doi.org/10.1186/s13578-022-00902-7