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Aberrant methylation of Serpine1 mediates lung injury in neonatal mice prenatally exposed to intrauterine inflammation

BACKGROUND: Intrauterine inflammation (IUI) alters epigenetic modifications in offspring, leading to lung injury. However, the epigenetic mechanism underlying IUI-induced lung injury remains uncertain. In the present study, we aim to investigate the effect of IUI on lung development, and to identify...

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Detalles Bibliográficos
Autores principales: Yao, Dongting, Zhao, Jiuru, Zhang, Qianqian, Wang, Tao, Ni, Meng, Qi, Sudong, Shen, Qianwen, Li, Wei, Li, Baihe, Ding, Xiya, Liu, Zhiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9526974/
https://www.ncbi.nlm.nih.gov/pubmed/36183130
http://dx.doi.org/10.1186/s13578-022-00901-8