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Aberrant methylation of Serpine1 mediates lung injury in neonatal mice prenatally exposed to intrauterine inflammation
BACKGROUND: Intrauterine inflammation (IUI) alters epigenetic modifications in offspring, leading to lung injury. However, the epigenetic mechanism underlying IUI-induced lung injury remains uncertain. In the present study, we aim to investigate the effect of IUI on lung development, and to identify...
Autores principales: | Yao, Dongting, Zhao, Jiuru, Zhang, Qianqian, Wang, Tao, Ni, Meng, Qi, Sudong, Shen, Qianwen, Li, Wei, Li, Baihe, Ding, Xiya, Liu, Zhiwei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9526974/ https://www.ncbi.nlm.nih.gov/pubmed/36183130 http://dx.doi.org/10.1186/s13578-022-00901-8 |
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