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The myosin II inhibitor, blebbistatin, ameliorates pulmonary endothelial barrier dysfunction in acute lung injury induced by LPS via NMMHC IIA/Wnt5a/β-catenin pathway

Acute lung injury (ALI) or its most advanced form, acute respiratory distress syndrome (ARDS), is a severe inflammatory pulmonary process triggered by varieties of pathophysiological factors, among which endothelial barrier disruption plays a critical role in the progression of ALI/ARDS. As an inhib...

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Detalles Bibliográficos
Autores principales: Zhang, Jiazhi, Pan, Ziqian, Zhou, Jianhao, Zhang, Ling, Tang, Jiahui, Gong, Shuaishuai, Li, Fang, Yu, Boyang, Zhang, Yuanyuan, Kou, Junping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9527152/
https://www.ncbi.nlm.nih.gov/pubmed/35716767
http://dx.doi.org/10.1016/j.taap.2022.116132