Atypical induction of HIF-1α expression by pericellular Notch1 signaling suffices for the malignancy of glioblastoma multiforme cells

Contact-based pericellular interactions play important roles in cancer progression via juxtacrine signaling pathways. The present study revealed that hypoxia-inducible factor-1α (HIF-1α), induced even in non-hypoxic conditions by cell-to-cell contact, was a critical cue responsible for the malignant...

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Detalles Bibliográficos
Autores principales: Lee, Jungwhoi, Kim, Eunsoo, Chong, Kyuha, Ryu, Seung-Wook, Kim, Chungyeul, Choi, Kyungsun, Kim, Jae-Hoon, Choi, Chulhee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9527190/
https://www.ncbi.nlm.nih.gov/pubmed/36183290
http://dx.doi.org/10.1007/s00018-022-04529-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9527190/
https://www.ncbi.nlm.nih.gov/pubmed/36183290
http://dx.doi.org/10.1007/s00018-022-04529-2

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